Topic: Optical Mapping of Cardiac Arrhythmias.

Speaker: William M. Smith, Professor and Interim Chair, Dept. of Biomedical Engineering, University of Alabama at Birmingham

Date & Time: Thursday, Aug 26, 2004, 1:00 PM

Place: Room 137 VMC (Chambers Hall)



Sudden cardiac arrest is one of the most devastating clinical problems in the industrialized world. The underlying mechanism of this problem is typically the breakdown of the organized electrical activity in the cardiac tissue. Cardiac arrhythmias have been studied in a variety of ways. Traditionally, mapping of cardiac electrical activity has been accomplished through the application of electrodes and the acquisition and analysis of the resulting signals. More recently, optical methods have been used to visualize approximations of the cellular transmembrane potential at many sites on the heart surface. There are currently attempts to develop techniques to make optical measurements within the tissue for true three-dimensional reconstruction of activation sequences. This lecture will describe limitations of electrical mapping, current attempts at three dimensional optical mapping, and potential future directions in this important interdisciplinary area.



Dr. William M. Smith is Professor and Interim Chair of the Department of Biomedical Engineering at the University of Alabama at Birmingham. He holds a secondary appointment in the Department of Medicine, Division of Cardiovascular Disease. Dr. Smith's primary research interests are cardiovascular signal processing and instrumentation, especially as applied to cardiac activation mapping and the study of cardiac arrhythmias and sudden cardiac death. He has also worked in cardiovascular image processing and computer graphics. His research is supported primarily through grants from the National Institutes of Health. He is a Fellow of the Institute of Electrical and Electronics Engineers (IEEE) and the American Institute for Medical and Biological Engineering.

Refreshments will be served at 12:45 PM

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